Position an oven rack in the middle and preheat the oven to 400°F (200°C). Line a baking tray or sheet with parchment paper. Place the salmon, skin side down, on the prepared baking sheet, and set it aside for further cooking.
In a small bowl mix together the mayonnaise, Dijon mustard, garlic, Italian seasoning, salt and pepper.
Spread it over the salmon.
In a separate small bowl, combine the breadcrumbs, Parmesan cheese and parsley. Pour in the melted butter and season with 3/4 teaspoon of salt and 1/3 teaspoon of pepper (adjust to taste). Mix the ingredients together and allow the breadcrumbs to absorb the butter.
Spread the mixture over the salmon, gently pressing it onto the top of the fillet to ensure it's fully coated.
Bake uncovered for 12-15 minutes, adjusting the time based on the thickness of your fillet. Look for a golden crust and ensure the salmon is cooked and flakes easily with a fork.
Serve it with lemon wedges and add a squeeze of lemon if desired. Pair it with a salad, steamed vegetables, rice, or mashed potatoes for a complete meal.
Enjoy!